CYRAMZA® (ramucirumab)

Update your billing and coding systems to include the permanent CYRAMZA® (ramucirumab) J-code: J9308, injection, ramucirumab, 5 mg. Issued by the Centers for Medicare & Medicaid Services (CMS), this permanent J-code is effective as of January 1, 2016.

CYRAMZA® (ramucirumab)



Patients who are prescribed CYRAMZA for its approved indications may be eligible for reimbursement services, financial assistance, or replacement product through the Lilly Cares Foundation.*

The Lilly Cares Foundation, Inc., an independent nonprofit organization, provides free Lilly medications to qualifying patients. Lilly PatientOne collects information on behalf of Lilly Cares to assist Lilly Cares with its charitable mission. For more information about Lilly Cares, please visit

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Billing Information Ordering Information
Code Description Setting
C9025 Injection, ramucirumab
5 mg vial
Hospital outpatient
J9308 Injection, ramucirumab, 5 mg Physician office
J9999 Not otherwise classified, antineoplastic drugs Physician office
J3490 Unclassified drugs Physician office
J3590 Unclassified biologics Physician office
Vial Size 100 mg/10 mL 500 mg/50 mL
NDC 00002-7669-01 00002-7678-01
Diagnosis Codes
Colorectal cancer
ICD-9-CM ICD-10-CM Description
Malignant neoplasm of colon
153.0 C18.3 Hepatic flexure
153.1 C18.4 Transverse colon
153.2 C18.6 Descending colon
153.3 C18.7 Sigmoid colon
153.4 C18.0 Cecum
153.5 C18.1 Appendix
153.6 C18.2 Ascending colon
153.7 C18.5 Splenic flexure
153.8 Other specified sites of large intestine
153.9 C18.9 Colon, unspecified
C18.8 Overlapping sites of colon
Malignant neoplasm of rectum, rectosigmoid junction, and anus
154.0 C19 Rectosigmoid junction
154.1 C20 Rectum
154.8 Other sites of rectum, rectosigmoid junction, and anus
C21.8 Overlapping sites of rectum, anus, and anal canal
Gastric cancer
ICD-9-CM ICD-10-CM Description
Malignant neoplasm of stomach
151.0 C16.0 Cardia
151.1 C16.4 Pylorus
151.2 C16.3 Pyloric antrum
151.3 C16.1 Fundus of stomach
151.4 C16.2 Body of stomach
151.5 C16.5 Lesser curvature of stomach, unspecified
151.6 C16.6 Greater curvature of stomach, unspecified
151.8 C16.8 Overlapping sites of stomach
151.9 C16.9 Stomach, unspecified site
Non-small cell lung cancer
ICD-9-CM ICD-10-CM Description
162.0 C33 Malignant neoplasm of trachea
162.2 C34.00 - unspecified Malignant neoplasm of main bronchus
C34.01 - right
C34.02 - left
162.3 C34.10 - unspecified Malignant neoplasm of upper lobe, bronchus, or lung
C34.11 - right
C34.12 - left
162.4 C34.2 Malignant neoplasm of middle lobe, bronchus, or lung
162.5 C34.30 - unspecified Malignant neoplasm of lower lobe, bronchus, or lung
C34.31 - right
C34.32 - left
162.8 C34.80 - unspecified Malignant neoplasm of other parts of bronchus or lung (overlapping sites)
C34.81 - right
C34.82 - left
162.9 C34.90 - unspecified Malignant neoplasm of bronchus or lung, unspecified
C34.91 - right
C34.92 - left
Drug Administration CPT® Code
Code Description
96413 Chemotherapy administration, intravenous infusion technique; up to 1 hour, single or initial substance/drug

Lilly and the Lilly Cares Foundation have contracted with a network of specialty distributors and one specialty pharmacy to provide customers access to CYRAMZA.

If purchasing CYRAMZA directly, you may use the four specialty distributors listed here. You also have the option of ordering from our authorized specialty pharmacy partner shown below. For more information on purchasing, dispensing, or returning Lilly products, visit For inquiries about this matter, contact Lilly at 1-800-LillyRx (1-800-545-5979).

Specialty Distributor Network
AmerisourceBergen Specialty Group
Order Entry Codes: 100 mg/10 mL - 42792, 500 mg/50 mL - 42793
Oncology Supply ASD Healthcare
P: (800) 633-7555, F: (800) 248-8205
P: (800) 746-6273, F: (800) 547-9413
Cardinal Health Specialty Pharmaceutical Distribution
Order Entry Codes: 100 mg/10 mL - 4982419, 500 mg/50 mL - 4982435
Oncology Clinics Hospitals
P: (855) 740-1871, F: (888) 345-4916
P: (866) 476-1340, F: (888) 345-4916
McKesson Specialty Care Distribution Corporation
Order Entry Codes: 100 mg/10 mL - 983-231, 500 mg/50 mL - 983-232
McKesson Specialty Health McKesson Plasma and Biologics
P: (800) 482-6700, F: (800) 289-9285
P: (877) 625-2566, F: (888) 752-7626
Smith Medical Partners
Order Entry Codes: 100 mg/10 mL - 375-8307, 500 mg/50 mL - 375-8315
P: (800) 292-9653, F: (630) 227-9220,
Authorized Specialty Pharmacy
Biologics Inc.
P: (800) 850-4306, F: (800) 823-4506,

Prescribing Information including BOXED WARNINGS

This information is presented for informational purposes only and is not intended to provide reimbursement or legal advice. Laws, regulations, and policies concerning reimbursement are complex and are updated frequently. Individual coding decisions should be based upon diagnosis and treatment of individual patients. Eli Lilly and Company does not guarantee success in obtaining insurance payments. While we have made an effort to be current as of the issue date of this website, the information may not be as current or comprehensive when you view it. Providers are encouraged to contact third-party payers for specific information on their coverage, coding, and payment policies. Please consult with your legal counsel or reimbursement specialist for any reimbursement or billing questions. For more information please call the Lilly PatientOne Program at 1-866-472-8663.

The Centers for Medicare & Medicaid Services assigned a 5 mg billing unit for CYRAMZA. The total dose of CYRAMZA (in milligrams) should be divided by 5 to get the correct number of billable units.

† FDA standard NDC has been “zero-filled” to ensure creation of an 11-digit code that meets HIPAA standards. The zero-fill location is indicated in bold.